Abstract
Responses to local light stimulation (LS), transcorneal electrical stimulation (TES), optic chiasm stimulation (OX), and suprachroidal-transretinal stimulation (STS) before and after tetrodotoxin intravitreal injection were analyzed with independent component analysis (ICA). The responses were imaged by ophthalmoscopes modified for consecutive near infrared imaging. Time and spatial information was obtained by obtaining the images before and after the stimulus. The time and spatial information consists of several responses with different origins and noises not related to the stimulus. We used spatial ICA to separate spatial components from compounded signals. ICA applied to the data from three anesthetized cats and comparisons with previous researches revealed that origin of response of LS and STS is hemodynamics in the outer retinal and that of TES and OX is blood flow in the retinal artery. Two independent components were found in ICA of TES and those were different in time and spatial characteristics.
