Serum total proteins, albumin and albumin globulin ratio in Yankasa sheep experimentally infected with Trypanosoma congolense and immunomodulated with levamisole

Abstract

Serum total protein, albumin and albumin globulin ratio were determined in Yankasa sheep experimentally infected with Trypanosoma congolense and immunomodulated with levamisole. The packed cell volume decreased significantly (P<0.05) between the infected groups with and without immunodulation with levamisole when compared to the controls. Serum total protein and albumin decreased significantly (P<0.05) in the infected groups with and without immunomodulation when compared to the controls. The differences between the infected groups with and without immunomodulation was not significant (P>0.05). Albumin globulin ratio decreased significantly (P<0.05) in the infected group with and without immunomodulation when compared to the controls but the difference was not significant (P>0.05) between the infected groups with and without immunomodulation. Generally, levamisole administration did not alter the course of the infection in Yankasa sheep when compared to the infected group without immunomodulation. The experimental period lasted six weeks.