The Journal of Protozoology Research
Online ISSN : 2434-7027
Print ISSN : 0917-4427
In Vitro Observations on Drug Responsiveness of Babesia bovis and on the Emergence of Drug Resistant Parasites
PEERAPAN TAN-ARIYAUSA CHETANONDCHARIA R. BROCKELMAN
Author information
JOURNALS OPEN ACCESS

1992 Volume 2 Issue 1 Pages 1-9

Details
Abstract

Four culture lines of Babesia bovis Thai strain were successfully established in this study. The results of the in vitro microtest for their sensitivities to quinuronium sulfate revealed that all the culture lines were similarly drug responsive. The 50% inhibitory concentrations for the four culture lines were found to be within the same range, varying from 1.72x10-6 to 2.43x10-6 g/ml. One resistant line TS-2R selected from the drug-treated culture had an IC50 of 1.71x10-5 g/ml which was 7 times higher than that of its original isolate TS-2.

Information related to the author
© 1992 National Research Center for Protozoan Diseases, National University Corporation Obihiro University of Agriculture and Veterinary Medicine
Next article
feedback
Top