Journal of Plastic and Reconstructive Surgery
Online ISSN : 2436-259X
Case Report
A Case of Dystrophic Epidermolysis Bullosa Treated with Meek Technique and Cultured Epithelial Autografts
Norihito Ito, Takako Komiya, Maiko Asai, Nanako Ayabe, Mai Hanano, Kohhei Aoki, Kazuki Shimada, Hajime Matsumura
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JOURNAL OPEN ACCESS

2026 Volume 5 Issue 2 Pages 112-116

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Abstract

Dystrophic epidermolysis bullosa (DEB) causes extensive blisters and erosions due to a genetic abnormality, significantly reducing patients' quality of life. Recently, transplantation of reversion-mutated mosaicized skin has shown promise as a radical cure. In 2019, the use of cultured epithelial autograft for DEB was approved in Japan.

Meanwhile, the Meek micrografting technique, first described in 1958 by Dr. Cicero Parker Meek in the United States of America, was reintroduced in 2019 as a new device for split-thickness skin grafting. This system can harvest skin grafts more efficiently than conventional methods.

In this case report, we report on our successful treatment of DEB using the Meek technique and cultured epithelial autografts.

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© 2026 Japan Society of Plastic and Reconstructive Surgery

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