Journal of the Physical Society of Japan
Online ISSN : 1347-4073
Print ISSN : 0031-9015
ISSN-L : 0031-9015
Formation and Stability of a Memory State in the Immune Network
Takashi Sonoda
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1992 Volume 61 Issue 4 Pages 1408-1424

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Abstract
The immune system is investigated as a complex adaptive network. A nonlinear dynamical model is proposed to study roles of lymphocyte and antibody in the regulation of the immune response. Three kinds of lymphocytes; B cell, TH cell, and TS cell, interact and compose a functional unit. Furthermore this unit interacts with other units through antibodies. These two types of interactions cooperatively work and regulate the immune response. The model can explain how the memory state is formed and stabilized in the immune network. Behaviors of the model are verified by the computer simulations.
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