Application of Clinical Pharmacology in Early Clinical Drug Development: PK/PD studies of a new proton pump inhibitor

Hongyun Wang

doi:10.1254/jpssuppl.94.0_3-S32-3

The 94th Annual Meeting of the Japanese Pharmacological Society

Session ID : 94_3-S32-3

DOI https://doi.org/10.1254/jpssuppl.94.0_3-S32-3

Conference information

Host: The 94th Annual Meeting of the Japanese Pharmacological Society

Name : The 94th Annual Meeting of the Japanese Pharmacological Society

Number : 94

Location : Sapporo

Date : March 08, 2021 - March 10, 2021

The 8th Japan-China Joint Meeting of Basic and Clinical Pharmacology

Application of Clinical Pharmacology in Early Clinical Drug Development: PK/PD studies of a new proton pump inhibitor

Hongyun Wang

Author information

CONFERENCE PROCEEDINGS OPEN ACCESS

Details

Abstract

Clinical pharmacology is critical in drug development. This presentation introduces the current status of its application in China, and then presents a PK/PD model for proton-pump inhibitor (PPI) drugs. This mechanism-based model is established using ilaprazole as a case drug in which food effect and circadian rhythm are taken into account, and it provides a potential strategy to accelerate the development of novel PPIs.

Corresponding author

Conference information

Register with J-STAGE for free!