Host: The Japanese Pharmacological Society
Name : The 97th Annual Meeting of the Japanese Pharmacological Society
Number : 97
Location : [in Japanese]
Date : December 14, 2023 - December 16, 2023
As the brain has a high degree of functional specialization and is highlyintegrated at various hierarchies, it is necessary to investigate anatomical andfunctional brain networks unbiasedly and independently of any foreseenhypothesis to elucidate the pathophysiology of brain diseases. To address theissue, we have developed a highly scalable and high-speed imaging system(block-FAce Serial microscopy Tomography, FAST) and methods to comparestructures and neural activity among individual animal groups. Using thesemethods, we are examining anatomical structure and neuronal activity changes inanimal disease models and those administered with therapeutic drugs. In thissymposium, I will introduce our recent progress and discuss the directions offuture research that would contribute to a better understanding of brain systemsand disorders.