Proceedings for Annual Meeting of The Japanese Pharmacological Society
Online ISSN : 2435-4953
The 97th Annual Meeting of the Japanese Pharmacological Society
Session ID : 97_2-B-S22-4
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Symposium
The need to consider ethical, legal and social issues (ELSI) in "Mibyo" (pre-symptomatic conditions) research
*Kamisato Ayako
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CONFERENCE PROCEEDINGS OPEN ACCESS

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Abstract

There is a gap of about 10 years between Japan's average life expectancy and healthy life expectancy. In recent years, to shorten this period, "mibyou" and its improvement have been attracting attention. There are various approaches to improve "mibyou", including dietary habits and exercise. In the Aihara Project of JST Moonshot Research and Development Project Goal 2, research is being conducted to mathematically define the pre-symptomatic conditions before the transition from a healthy state to a diseased state, and to realize ultra-early disease prediction and prevention. This is a major challenge that has the potential to change the concepts of "health" and "disease." Therefore, it is also necessary to consider the impact on society if this becomes a reality. In addition, research involves the collection of a large amount of data from patients, therefore it is necessary to gain the public's understanding of the necessity of research and to provide sufficient and appropriate explanations regarding the research to patients. For this reason, the project has established an ELSI support team that examines legal, ethical, and social issues (ELSI) and supports researchers. In this presentation, I will show the results of the questionnaire survey that we conducted in 2022 and discuss ELSI in pre-symptomatic research, taking into consideration issues that are often pointed out regarding the realization of genomic medicine.

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