Human pluripotent stem cells in neurological disease modeling and drug discovery

Abstract

The iPSC technology was established a decade ago, and enormous progress in stem cell medicine has since been made. Human iPSC-derived cells has been used for multiple purposes including disease modeling and cellular transplantation. New drugs originating from iPSC screens are in the pipeline. Furthermore, the combination of iPSC technology with recent developments including CRISPR technology makes iPSC-based platforms even more robust in each area of their application. In this lecture, I talk about human pluripotent stem cells in neurological disease modeling and drug discovery.