Proceedings for Annual Meeting of The Japanese Pharmacological Society
Online ISSN : 2435-4953
WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology)
Session ID : WCP2018_OS-2
Conference information

Opening Symposium
Translational medicine, pharmacology and drug discovery
Garret A. FitzGerald
Author information
CONFERENCE PROCEEDINGS OPEN ACCESS

Details
Abstract

Although 46 drug approvals by the FDA in 2017 was the highest in 20 years, drug development remains a highly inefficient process with a declining rate of return on investment. Public pressure and the decline in spending power by the NIH have fostered in the US engagement of academia in translational science. This requires investment in human capital pertinent to understanding the mechanisms of drug action and the factors contributing to variability in drug response. Additional challenges are the development of organizational and physical infrastructure to support the deep phenotyping characteristic of human phenomic science and its integration with data derived at scale from electronic health records and linked biobanks. Novel approaches to collaboration with industry, addressing issues of conflict of interest and patent coverage can facilitate access to expertise in medicinal chemistry and kinetic modelling.

Content from these authors
© 2018 The Authors(s)
Previous article Next article
feedback
Top