Isolation and Purification of Cyclomaltononaose (δ-CD) from CELDEX SG-30

Abstract

Cyclomaltononaose (δ-cyclodextrin, δ-CD) is a member of the cyclomaltoses and is composed of nine α-(1→4)-linked ^d-glucopyranose units. Though it has already been purified from commercially available CD powder, DEXY PEARL K-50, the yield was very low. To improve the yield of δ-CD, we tried to isolate and purify it from a new CD source, CELDEX SG-30, and the final product was identified as δ-CD by HPLC and FAB-MS. Further, the yield from CELDEX SG-30 was superior to that from DEXY PEARL K-50.