Abstract
Histochemical demonstration of prostaglandin dehydrogenase activity in hamster eggs during their folliculogenesis was made using PGE2 or PGF2α, as the substrate according to the method of NISSEN and ANDERSEN. The enzyme activity was negative in the eggs in primary follicles, but became positive in those in small secondary follicles though the activity was rather weak. The activity which was still weak in the eggs in large secondary follicles had grown much stronger in those in antral follicles. The results thus show that prostaglandin metabolism may be absent in hamster eggs at their earlier stages of folliculogenesis, but becomes stronger during the later stages of it.
