Abstract
Radiation health risk estimation for radiation protection is based upon the epidemiological data of acute-exposure to relatively high-dose and high-dose rate radiation, and therefore, requires an extrapolation to low-dose and -dose rate to apply to the practical doses of radiation protection. The reduction factor is estimated by long-term animal experimental data and the numerical model analysis. Therefore, the storage of animal exposure experiment data and the reposition of derivative biomaterials of both passed and present studies are valuable and important. NIRS have started the archival and repository activities to collect, digitalize and storage the data/materials of long-term animal experiments. Activity includes the collection and digitalization of the primary data and information (detail exposure protocols, animal data and pathological diagnosis, etc.) and storage of the experimental materials (paraffin embedded tumor blocks, derivative slides). We here report the results of preliminary dose-response analysis of our archival data (C3H mouse) below 1Gy. [J Radiat Res 44:405 (2003)]
