The Japan Radiation Research Society Annual Meeting Abstracts
The 47th Annual Meeting of The Japan Radiation Research Society
Session ID : 2M-07
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Radiation Protector and Sensitizer
Inhibition Effects of Ginseng on Proliferation of Enteric Corynebacterium Kutcheri in Irradiated mice
*Masayoshi SaitoTomonori IsobeTomoko IsobeTetsuya KawataHisao Ito
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Abstract
Inhibition effects of ginseng on proliferation of the infectious Corynebacterium Kutcheri of the caecum in the whole body irradiation mice were studied. The mice (male ICR, 5weeks of age) were exposed to X rays (125Kv,217cGy/min) of 3 to 6Gy and were infected with Corynebacterium Kutc-heri peroral(p.o.). These mice were given 30% EtOH extract of ginseng p.o. at 40mg/0.2ml/mouse every other days for 5 times. The results obtained in the present study were as follows. 1. The bacteria count in the caecum and detection rate of the bacteria in the oral cavity, tracheal region of mice were increased in proportion to exposure dose. 2. The bacteria counts in the caecum and positive detection rate of the bacteria in the oral cavity, tracheal region of mice were decreased in the ginseng administration groups. 3. Life prolongation of the ginseng administration mice was increased, compared to the experiment control(irradiation + infection, no administration of ginseng. on the day 10 after irradiation).
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© 2004 The Japan Radiation Research Society
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