Host: The Japan Radiation Research Society
Co-host: Asian Association for Radiation Research
A classical paradigm of radiation biology asserts that all radiation effects on cells, tissues and organisms are due to the direct action of radiation. However, there has been a recent growth of interest in the indirect actions of radiation including the radiation-induced adaptive response, the bystander effect, low-dose hypersensitivity, and genomic instability, which are specific modes of stress exhibited in response to low-dose/low-dose rate radiation. Having become one of the triggers of this concern is development of the microbeam irradiation device that enables aim to be irradiated and advancement as for one cell. The research for the radiation-induced bystander effects using the microbeam irradiation device is actively done in Japan, USA and UK, and then many findings about the radiation-induced bystander effects have been accumulated.
Here, I would comprise recent research for radiation-induced bystander effects and the adaptive response, and discuss the contribution of the former to the latter.
