Abstract
Radiation protection effect and an anti-tumor effect are recognized in AHCC educts by a precedence study, and, as for the action mechanism, a thing by immunization activity action and anti-oxidation action is made clear. In this study, we reviewed an anti-tumor effect with radiation exposure and presence of protection effect of immunization degradation by combined effect in anti-oxidation action and radiation with AHCC. We did oral of each AHCC 250mg/kg every other day for two weeks after having inoculated about 2*106 Scc-7 into ICR mice. In addition, we measured weight and tumor size later for cancer cell seeding two weeks. Furthermore, in AAPH method, we measured anti-oxidation action. As the days passed in the group that they inoculated only a cancer cell into, the tumor size increased, but decrease of tumor size to be clear in radiation independent exposure group and a AHCC and radiation combination group was recognized. It was the crowd whom they inoculated only a cancer cell into after exposure two weeks, and 2/3 lived in AHCC and radiation combination group for what died almost. In addition, the leukocyte, the lymphocyte count increased by the dosage of AHCC regardless of presence of radiation exposure. In addition, anti-oxidation action was clear, too. It think that we can contribute to an immunological enhancement effect in radiation cancer therapy and side effect prevention in addition to protective effect and a cure effect of cancer by taking in a AHCC.
