Host: The Japan Radiation Research Society
To protect normal tissues from radiation-induced damages, usage of radioprotector is one possible way. The properties of radioprotectors required should be different depending on what occasion they are used. When they are used on the occasion of radiation exposure from nuclear accidents and radiological terrorism, which could result in large-scale casualties, the properties required are, for example, 1) effectiveness of post-irradiation administration, 2) easiness for administration, 3) stable and inexpensive. On the occasion of clinical use of radiation, the protectors can be administered before irradiation. When protectors are used for radiation therapy to reduce normal tissue damages, they should not protect tumors. When protectors are used for radiation diagnosis, they should be free of side effect, because they are used for a large number of normal subjects. In the present symposium, the present status of development of various kinds of radioprotectors including the results of our group will be shown.