New aspects of cancer therapies targeting signal transduction pathways from bench to bed

Abstract

In recent, we can find many advanced reports about signal transduction pathways of cell survival, DNA repair, cell cycle and angiogenesis of cancer cells. These pathways were induced after the cancer cells were treated with cancer therapies. To aim much high efficacy in cancer therapies, It is important to control these pathways. In this symposium, we aim to introduce new advanced experimental results targeting these pathways from basic research and combine to cancer therapies for patients. For example, we schedule to presentation and discussion about the control for cell survival signal and cell cycle signal such as mTOR, the depression for DNA repair and the sensitization among radiation, hyperthermia and anti-cancer drugs.