The study of the evaluation method for the model rats for consideration of Hypoxic-Ischemic Encephalopathy therapeutic effect due to Atmospheric-pressure plasmas.

Abstract

Atmospheric-pressure plasmas can disinfecting and disintegrating hazardous materials and modifying material surfaces. Although the mechanism of action remains unclear, new biomedical applications of plasma have been found. We believe that the mechanism of plasma should be clarified. Plasma technologies have diverse applications, such as skin regeneration by multiple low-energy plasma therapy. On the other hand, hypoxic-ischemic encephalopathy (HIE) is a condition in which the brain does not receive enough oxygen. When brain cells fall into the acid deficient state, it begins to death in just less than 5 minutes. Cause of HIE is various, for example, respiratory failure and circulatory failure, neonatal asphyxia. We want to conduct an experiment on the functional recovery of the HIE by atmospheric pressure plasma inhalation. We guessed the effect of the plasma to the HIE model rats, was studied evaluation method.