Abstract
For the realization of a wearable artificial kidney, the filtrationadsorption method with continuous low filtrate flow is suitable. For a filter for this use, a plasma separator is advantageous as regards the miniaturization of the filtration equipment. A parallel flow type plasma separator was designed based upon the relationship between filtrate flux and shear rate. To miniaturize the device, the blood cistern was laminated and in vivo experiments with dogs were performed. Filtrate flow rate was lower than the value of the design specification. From this result, some problems to be considered in more practical design were examined.