Experimental Study of Modified Human Saphenous Vein Homografts

Abstract

Twelve glutaraldehyde- tanned human saphenous veins (GHSV), fourteen ficin-treated glutaraldety-de-tanned human saphenous veins (FGHSV), and ten gore-tex were implanted in the abdominal aorta of dogs. The patency rate was 83% (GHSV), 85% (FGHSV), and 80% (Gore-tex).
Two GHSV and Two FGHSV had so high ant igenicity that we found no thrombus on their surface and microscopically their structure were as same as they were implanted more thane 1 year ago. We conclud that modified human saphenous vein homografts are reliable to use as a small calibar arterial substitutes.