Abstract
Activated charcoal has been used as an adsorbent for direct hemoperfusion in the treatment of drug intoxication, renal and hepatic failure. None of charcoal materials presently employed were not satisfactory.
We developed a new type of activated charcoal to improve its adsorbability. This material is made of micro-activated charcoal, its diameter ranging from 0.5 to 0.7mm, the effective surface area being 1, 300m2/gr and macro-polus being (more than 50Å) 20m2/gr.
In the present study, in vitro and in vivo adsorption of Cr, Vit B, Bilirubin and amino acids including tyrosin, phenylalanin, valin and leucin, was tested with this material.
It was concluded that the new charcoal was superior in adsorbability to conventional charcoal and it was particularly effective in the selective adsorption of aromatic amino acids.
