Abstract
Effect of crystallinity of polyamides on blood coagulation were investigated in terms of adhesion behavior of blood platelets. Polyamides having various crystallinity were synthesized and were annealed after coating on the glass beads. Then, platelets adhesion on these polyamides was evaluated by Microsphere column method. It was found that there was a correlation between adhesivity of platelets and crystallinity of polyamide. Transmission electron microscopic observation revealed that these polyamide surfaces formed microdomain structure composed of crystalline domains and amorphous domains. From these results, it was concluded that the distribution of microdomains (crystalline-amorphous) played an important role in platelets adhesion.
