人工膵臓 ―血液直接測定型グルコースセンサーの臨床応用―

市川 健次; 湯川 孝雄; 大倉 国利; 市橋 秀仁; 近藤 達平; 小島 洋彦; 沢田 雄治; 池田 章一郎; 伊藤 要; 山崎 親雄; 増子 和郎

doi:10.11392/jsao1972.10.1105

Artificial Pancreas

-Clinical application of the new glucose sensor-

K. ICHIKAWA, T. YUKAWA, K. OOKURA, H. ICHIHASHI, T. KONDO, H. KOJIMA, Y. SAWADA, S. IKEDA, K. ITO, C. YAMAZAKI, K. MASUKO

Author information

K. ICHIKAWA
The 2nd Department of Surgery, Nagoya Univercity School of Medicine
T. YUKAWA
The 2nd Department of Surgery, Nagoya Univercity School of Medicine
K. OOKURA
The 2nd Department of Surgery, Nagoya Univercity School of Medicine
H. ICHIHASHI
The 2nd Department of Surgery, Nagoya Univercity School of Medicine
T. KONDO
The 2nd Department of Surgery, Nagoya Univercity School of Medicine
H. KOJIMA
The 1st Department of Surgery, Aichi Medical College
Y. SAWADA
Department of Synthetic Chemistry, Nagoya Institute of Technology
S. IKEDA
Department of Synthetic Chemistry, Nagoya Institute of Technology
K. ITO
Department of Synthetic Chemistry, Nagoya Institute of Technology
C. YAMAZAKI
Masuko Hospital
K. MASUKO
Masuko Hospital

Keywords: Artificial pancreas, Glucose sensor, Enzyme electrode, Blood glucose

JOURNAL FREE ACCESS

1981 Volume 10 Issue 6 Pages 1105-1108

DOI https://doi.org/10.11392/jsao1972.10.1105

Details

Abstract

The vessel access type glucose sensor for the implantable artificial pancreas has been developed in our labolatories. The sensor is connected to a vessel access through which the blood flows and enable to measure blood glucose levels without sampling and diluting blood.
Clinically, the sensor was applied on renal failure patients using hemodialysis circuit. The sensor responded well in parallel with the blood glucose levels measured by Autoanalyser from 110 to 350mg/dl in increasing phase, however, at initial measurement it takes about 30 minutes' delay to response in decreasing phase.

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