Abstract
This experimental study compares the effects of pulsatile perfusion (N=6) with nonpulsatile perfusion (N=6) on hemodynamics and metabolism during about 2 hour's nonworking beating heart. Following results were obtained.
Myocardial blood flow, myocardial oxygen consumption, myocardial lactate extraction/myocardial oxygen consumption, systemic lactate extraction/systemic oxygen consumption and postperfusion's DPTI/TTI of pulsatile group were significantly higher than nonpulsatile group. Myocardial vascular resistance, Systemic vascular resistance, Systemic blood flow of pulsatile group were significantly lower than nonpulsatile group. The results demonstrate that the pulsatile perfusion in nonworking beating heart minimized the deleterious effects of nonpulsatile perfusion on hemodynamics and metabolism.
