Abstract
Microhemodynamic changes accompanying the intravenous injection of perfluorochemical emulsion (Fluosol-43, FC-43) as well as an emulsifier contained in that emulsion, i. e. Pluronic F-68, PF-68, were studied in the rat mesentery by means of an intravital television microscope. Experimental results revealed that a remarkable increase in capillary blood flow and an augmented leucocyte sticking along venular wall was induced in either case of the intravenous injection of FC-43 and PF-68, which suggest that the emulsifier plays a primary role in determining the microvascular behavior of the intravascularly infected PFC emulsion.
