Abstract
56-year-old male with malignant RA was treated by 6 plasma exchanges with prediluted plasmapheresis using the ASAHi PFO-02. Bloodaccess was gained from both cephalic vein of forearms for afferent and efferent line. The blood of flowrate 70ml/min was diluted by Hartman's solution, which was infused with flowrate 30ml/min by roller pump through the afferent line. As a result of dilution, blood flow for afferent line increased up to 100ml/min. After plasma exchange the titers of RAHA and ANA decreased. The sieving coefficients and filtration efficient of IgM did not tended to decrease with at least over 1 hour of perfusion.