Abstract
The transport characteristics of serum electrolytes (Nat, Cl-, K+) were clarified using four commercial dialyzers and a newly developed dialyzer using negatively chrged membranes.
The following resluts were obtained: (1) The permeability of potassium is slightly greater than that of sodium, which may be explained on the basis of diffusion coefficients and hydrated radii. (2) The transport mechanism of electrolytes in a dialyzer differs from that of non-electrolytes. (3) Transport of small uclecular electrolytes is little affected by a negatively charged membrane, but the membrane is completely impermeable to low nalecular weight protein, which is negatively charged in blood.