Abstract
We performed clinical comparative study of dialysis using protein permeable EVAL membrane and conventional cellulosic membrane, such as cuprophan and cellulose acetate. Removal ratio and clearance of small molecular solutes were low in EVAL membrane and high in cuprophan membrane. Whereas sieving coefficient of large molecular solutes was high in EVAL membrane and cuprophan membrane was not permeable to protein. Sieving coefficient of prolactin, albumin, transferrin, IgO and total protein was significantly higher inEVAL-C membrane than EVAL-D memrane. As eommon characteristic findings obserbed in EVAL-C and EVAL-Dmembrane dialysis, increase of platelet, WBC, phosphate, cholesterol and fibrinogen were obserbed. While decrease of serum creatinine and increase of serum calcium were obserbed in cuprophan membrane dialysis. Thus, from clinical course of 9 dialysis patients using various membranes, distinct and interesting differences were obserbed.
