Abstract
Osmotic fragility (OF) on RBC was studied for hemodialysis (HD) and hemofiltration (HF). Cellulose acetate membrane (CA) and cuprophane membrane (CP) were used for HD and CA was used for HF. The lowest OF was observed after HD using CA and secondly after HF using CA. 15 minutes after start of operation, however, the lowest OF was seen in CP. This time was equal when hemodialysis leukopenia occured, and some relationship was suggested between OF and hemodialysis leukopenia during hemopurification. No correlation was observed between OF and BUN or serum creatinine for each membrane, and clearance was lower in HF than HD. As for OF on RBC, HD using CA was seemed the best hemopurification.