Hybrid Arti fieiai Liver Using Hepatocytes

Abstract

For the basical research of hybrid artificial liver using hepatocytes, the activities and the maintenance of hepatocytes on several collagenous substrata were examined. The maintenance of hepatocytes on collagenous surfaces were better than non-coated PSt surface. Hepatocytes cultured on succinylated collagen surface had the most highest activities. Moreover, hepatocytes were cultured on hollow fiber in Artificial Capillary Culture Module.