Abstract
C3a, C4a and C5a were evaluated in three patients treated by PE using membrane plasma separator (MPS). C3a and C4a continuously increased in blood. Filtered plasma by MPS contained significantly higher concentration of C3a, C4a and C5a than blood. The continuous increase of C4a means the activation through the classical pathway in MPS. The activation by MPS differed from that by dialyzer.
