Abstract
Filtration characteristics of EVAL secondary filters were studied in vitro tests by using diseases plasma with varying plasma composition. The filtrate volume processed was dependent upon plasma types. Stable and constant sieving for each solutes were achieved independent of transmembrane pressure and filtrate volume. Transmembrane pressure showed the good correlation to bulk concentration of total protein trapped in the filters irrespective of plasma types and membrane types. The filtration of flow direction from outside to inside of hollow fibers gave lower filtrate volume and unstable sieving to increasing transmembrane pressure compared to that from inside to outside. It is suggested that the microstructure of EVAL_ membrane would connect to filtration characteristics of EVAL filter.
