Abstract
We clinically evaluated the newly developed plasma filter which was composed of anisotropic porous follow fiber membrane with outer surface having smaller pore size than that of inner one. In this device, separated plasma flowed from outer surface of membrane to inner surface. The filter sharply removed the large molecular weight protein such as IgM and it also separated IgG with sufficient collection of albumin. The sieving coefficient of plasma components, transmembrane pressure and filtrated volume were maintained almost constantly during 4hr-treatment. The stableand long standing. filtration capacities were the most remarkable characteristics of this membrane. We conclude that this plasma filter can be widely available for clinical application.
