Abstract
This paperr describes our attempts to remove toxic substances from the patients plasma ex vivo, separation i t from the extracorporeal circulation, and immediately freeze the refined plasma before reusing it as the replacement fluid in the next plasma exchange. we refer to this system of plasma exchange as processed autol ogous fresh-frozen plasma (PAFFP). We regard plasma exchange using PAFFP as a very comfortable physiological and safe procedure for patients. When we finish to perform PCPP or DFPP, we collect the residual plasma in the extracorporeal circulation and use it as the substitute fluid in the next performance. We can spare about 300ml of substitute fluid in every plasmapheresis by using this method.
