Abstract
Effects of plasma exchange on acute pancreatitis were investigated experimentally and clinically. Serum amylase, lipase, phospholipase A2 levels decreased about 50% by 1600ml of plasma exchange in experimental acute pancreatitis. For 2-patients with acute pancreatitis, plasma exchange was performed. Serum pancreatic enzymes such as amylase, lipase, trypsin, elastase 1 decreased remarkably by 3000 or 4000ml of plasma exchange. Plasma exchange was effective for rapid removal of serum pancreatic enzymes in acute pancreatitis.