Clinical and experimental evaluation of albumin autoclaved preclotting of the graft

Abstract

Albumin autoclaved preclotting (AAP) was performed in the 23 grafts of 17 patents without extracorporeal circulations and 3 grafts in the dogs. PAP was simple and prevented blood leakage from even a Knitted Dacron graft. No thromboembolism was observed and all grafts were patent clinically. Scanning electron microscope revealed a thin and smooth fibrin layer formation in both the human and the dog experiments. Formation of an endothelial-like cell is to be checked after a long implantation. In conclusion, PAP is clinically useful and expected to have good healing of the graft surface.