Abstract
RV failure has been recognized as a complication of LHB. The purpose of this study was to characterize RV functional change which occured during varying LV volume load. 8 dogs were subjected to roller pump LHB while RV pressure, it's first derivative (dp/dt) and contractile force (Strain gauge, SG) were evaluated. The venous return to the RA (CO) was maintained at 100ml/kg/min with second roller pump, while both cavae were interrupted from the RA. AoP, LAP, RAP, RV dp/dt, RVSG and flows in both pumps were recorded. All measurements were compaired before and after the ligation of the septal perforator (SP). Conclusion: 1) The more complete the LV decompression the more detrimental the effect on RV function. 2) Increased volume load to the LV produces an increase in RV dp/dt, but a decreased SG. 3) After ligation of the SP, RV dp/dt was unaffected despite the increased LV volume. 4) These results suggest that RV dp/dt was influenced by the contractility of the septum. The detrimental RVSG, however, resulted from the change of LV geometry.
