Abstract
Shiley M-2000 membrane oxygenator contains heat exchange and 2.3m2 of microporous polypropylen membrane in parallel plate design. This membrane is used two Cellgard membrane, pore size 0.2×0.02μm and 0.4×0.04μm, which are placed cross one over the other. The element of Z-fold membrane are kept separated by the insertion of latticed polypropylene spacer in each gas and blood fold and provide bilevel crossflow. In vitro, the gas transfer performance and oxygenator resistance of M-2000 were proved to be better than those of CML, but heat exchange performance was lower than CML. Five clinical cases using M-2000 are compaired with the other four membrane oxygenator groups. There is no significant difference among four membrane oxygenators in the counts of platelet, white blood cell, microbubble and urine volume without plasma free hemoglobine, that is significantly low in CML.
