Abstract
We have studied the relation between blood LAL-RM of hemodialysis patients and dialyzers using Toxicolor Test. LAL-RM of patients who are just entering on maintenance hemodialysis reveal the same value as controls. LAL-RM of A (cuprophan dry type dialyzer) group is of high value after first hemodialysis, keeping high level hereafter. That of C (cellulose acetate or synthetic polymer membrane dialyzer) group does not change and B (cuprophan wet type dialyzer) group is between A and C groups. LAL-RM of three patients is measered in series on first hemodialysis. An elution of LAL-RM from membrane is observed at 15-30 minutes after starting hemodialysis. The LAL-RM in one an hour reaches nearly the same value as that three hours later. In the maintenance hemodialysis, LAL-RM is very high in A group and the same value as cotrols in C group. B group exhibits the midway. After exchange of dialyzer from A group to B or C group, the decrease of LAL-RM up to level of B or C might neccessity about three months. There is no relation between blood LAL-RM and hemodialysis terms in A group.
