Abstract
Sterilization strongly affects the permeability of dialysis membranes and their structure. The clearance of hemodialyzer composed of regenerated cellulose membranes with higher porosity is lowered by autoclave compared to the other sterilizations (Gamma-ray and EOG). Gamma ray sterilization under dry conditions greatly decreases the hydraulic permeability of regenerated cellulose membranes with lower porosity less than 50%. However, there exists no difference in the clearance of urea and creati ni ne among the varying sterilizations except that of VB12. Pore theory calculation reveals membrane shrinking resulted from Gamma-ray sterilization.
