Abstract
Interleukin-1, -2 (IL-1, IL-2) were well known as enhancing factors in immune response system. Ciclosporin (CYA) is a new potent immunosuppressive agent to allo-transplantation of kidney, liver and heart etc. The immunosuppressive effects of CYA was mainly inhibition of the synthesis of IL-1, IL-2. But, after the synthesis of IL-2, the immunosuppressive effect of CYA to immune response system was decreased sharply.
In this study, immunological adsorptive capability has been screened in 115 nonbiological materials by bioassay to IL-2 using IL-2 sensitive culture cell line (NKc-7).
