Experimental study in new sequential synchronize driving system of IABP and LVAD

Abstract

New sequential synchronize driving system of IABP and LVAD was developed and it's hemodynamic effectiveness, especially renal circulation, was evaluated, in swine. This system could easily change driving phase (optimal counterpulsation, early diastole, late diastole) and was expected to clinical application. Renal artery flow and regional renal blood flow was decreased by combination optimal counterpulsation mode of IABP and LVAD. This mode was thought to be harmful influence on renal function. But, delay devide combination mode (drived on early diastole and late diastole), using new system, resulted in no change in renal circulation. So, this delay devide combination mode appeared to be mose promising support to not only failed heart, but also renal circulation.