Abstract
Continuous Arteriovenous Hemofiltration (CAVH) is a blood purification technique in which electrolytes and water removal of patients with acute renal failure or multiple organic failure is easily controlled at bedside outside of hemodialysis facilties. In the present study, a portable CAVH assisting device, TR-510 was developed and clinically used in 4 patients with renal failure. The device can be used for CAVH and its modification safely and conveniently by controlling the volumes of both substitution solution and filtrate. The control precision in vitro and in vivo (represented in one patient) was presented as a total volume of measured filtrate. The figures were 9925±78.2ml and 117.7l respectively. The errors with the indicated levels in vitro and in vivo were 2.3±0.2% and 0.34% respectively. Therefore, the control precision was demonstrated to be excellent. The safety device acted without any troubles and the treatment was done with perfect safety. The new device is capable of a planned control of substitution solution and filtrate for CAVH and its modification. Therefore, a expansion of the use of the device for other therapies can be strongly expected.
