Abstract
Human thrombin (T) and Factor XIII (XIII) were irmobilized on biodegradable gelatin (G) by lyophilization, to provide a new material for hemostasis and wound healing, “G·T·XIII”. The efficacies of the material were evaluated in in vivo and clinical studies. Hernostasis with the material was ccrnpletce and the tissue adaptability was good, in the studies of liver biopy. Wound healing was remarkably promoted with the application of G·T·XIII.
All these suggest that G·T·XIII has a great potential for various clinical applications, such as hemostatics, thrambotic agents, wound dressings, and so on.
