ANTICOAGULATION FOR THE HEPATIC ASSIST SYSTEM USING FUT-175 AND DIPYRIDAMOLE

Abstract

Donor plasmapheresis was performed and the filtrated plasma of 300ml was obtained using nafamostat mesilate (FUT-175) and dipyridamole as anticoagulants.
Conbined use of FUT and dipyridamole was useful to prevent platelets depletions during plasmapheresis. In clinical use for the hepatic assist system, FUT was a useful anticoagulant for the patients who showed a hemorrhagic tendency.