GLYCEMIC CONTROL WITH THE ARTIFICIAL BETA CELL (ABC) DURING SURGICAL TREATMENT OF ACROMEGALY AND CUSHING'S DISEASE ASSOCIATED WITH SECONDARY DIABETES

Abstract

Clinical usefulness of the ABC is expected in cases with secondary diabetes for glycemic control during surgical treatment, but such clinical observations have not been previously reported. We applied the ABC to two patients (57y. o. woman with acromegaly and 34y. o. man with Cushing's disease) associated with secondary diabetes. In these cases, satisfactory glycemic control was achieved with the ABC for more than 48 hours during and after surgical treatment. The result indicates that the ABC is a useful device for glycemic control during surgical treatment of secondary diabetes in which an acute alteration of counter regulatory hormones against insulin occurrs.