Abstract
An on-line SAC plasmapheresis was desighned and carried out as a new SAC method which patient's plasma could be treated continuously during plasmapheresis. The method was applied for 4 chronic rheumatoid arthritis patients. The new method was clinically evaluated herewith. This therapy took within 3.5hr for the treatment of an average 2610ml of plasma and the operation was comparable to the doble filtration and cryofiltration methods. In the reduction rates of plasma total protein, albumin, IgG, IgA, IgM was 26.3±4.6%, 18.6±6.3%, 46.1±10.8%, 36.9±17.0%, 35.2±10.1%. The excessive NaCl and glycine as precipitants can be sufficiently removed by a 0.8m2 surface area dialyzer. The method provided safe and effective autamation of plasma exchange without any trouble therapy.
