Abstract
In order to obtain the formula to calculate the Donnan ratio (R) from protein concentration in plasma (Ctp) and sodium concentration in dialysate (D[Na]), the experimental equilibrium dialyses were performed in vitro. The formula was represented as follows:
R=1.0-αR×Ctp/D[Na] where αR is a constant.
The values of αR varied with the measurement methods for Na and Cl. The results indicated that when the Donnan equilibrium phenomenon was discussed, Na concentrations measured by flamephotometry and Cl by potentiometric titration should be used after the correction as to the complex-binding to albumin, and also suggested that Na and Cl concentrations by Ion-Selective Electrode should be carefully dealt with.
