Jinko Zoki
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
Effective Absorption of β2-Microglobulin by Absorbents
M. ABEH. URANOM. SUZUKIY. HIRASAWAY
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JOURNAL FREE ACCESS

1988 Volume 17 Issue 1 Pages 77-80

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Abstract
We had already revealed that same kinds of polypeptides and low molecular weight proteins were significantly removed fran the uremic plasma by the absorption mechanism on same dialysis membranes in vitro. In the present study, commercially available absorbent resins XAD-7, XAD-8, IRA-45, and IRC-50 showed the venous absorption properties for β2-MG, lysozyme, ribonuclease, myoglobin, retinol-binding protein, α1-microglobulin, glucagon, C and N-terminal PTH respectively. XD-4 had no absorption effects. Especially, XAD-7 and XAD-8 had the strong affinity to β2-MG. One gram of XAD-7 or XAD-8 were estimated to absorbe 0.90mg or 0.36mg of β2-MG respectively.
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© The Japanese Society for Artificial Organs
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